What are these pimples I can scratch out of my head that are sometimes attached to the base of hair fibers?

The pimple is probably hardened sebum. It is white or light yellow in color and if pressed hard can be squashed and molded. The sebum is made up of oils and material from the sebaceous gland attached to the hair follicle and from keratinized cell debris. People with many types of hair loss including androgenetic alopecia get these pimples. An affected hair follicle that does not produce hair fiber still has an active sebaceous gland and the hair follicle also still produces sheath cell material. These products combine to make these sebum plugs that you can pick out. Because the hair fiber is not growing or not growing properly there is less force pushing this stuff out of the hair canal so it can build up and form a sebum plug. Sometimes hair follicles that still have hair in them also make sebum plugs if the hair is not growing properly. Sebaceous glands can also be androgen sensitive and may be promoted into increased oil production. This can aggravate the problem with pore clogging sebum. Regular washing and very mild shampoo might help but for as long as the alopecia persists you will probably have these plugs in some hair follicles.

Understanding Scalp Pimples: Causes, Composition, and Management

Scalp pimples, often referred to by those who experience them as “pimples I can scratch out of my scalp” are a common concern that can be both uncomfortable and worrying. These pimples are typically hardened sebum plugs that can sometimes be attached to the base of hair fibers. They are associated with various types of hair loss, but they can sometimes be found in pattern hair loss / androgenetic alopecia. This article explores the underlying causes, composition, and potential management strategies for these scalp pimples.

Composition of Scalp Pimples: The primary component of these scalp pimples is sebum, an oily substance produced by sebaceous glands. Sebum is crucial for maintaining the health and hydration of both skin and hair. However, when it becomes hardened, it forms plugs that can be expelled from the scalp. These plugs are usually white or light yellow in color in Caucasians and Far East Asians, but can be darker yellow to brown color in Asians and Africans. Sebum plugs are composed of:

  1. Sebum: A mixture of lipids including triglycerides, fatty acids, wax esters, and squalene.
  2. Keratinized Cell Debris: Dead skin cells that have undergone keratinization, the process where cells become filled with keratin protein and die, forming a protective layer.
  3. Sheath Cell Material: Cells from the hair follicle inner root sheath that surround the hair shaft. The inner root sheath naturally breaks down towards the skin surface and sebaceous gland oils are actively involved in this breakdown process.

Common Causes of Sebum Plugs in Hair Follicles: Several factors contribute to the formation of sebum plugs in hair follicles:

  1. Inactive Hair Follicles: In conditions like androgenetic alopecia, hair follicles may stop actively producing hair fibers for prolonged periods of time. Despite this, the sebaceous glands remain active, continuing to produce sebum and cellular debris that accumulate and form plugs.
  2. Improper Hair Growth: Even when hair follicles are still producing hair, if the hair is not growing properly, or if the hair is progressing towards miniaturization, the natural process that pushes out sebum and cellular debris is reduced, leading to an increased likelihood of sebum plug formation.
  3. Androgen Sensitivity: Sebaceous glands can be sensitive to androgens (male hormones such as testosterone). Increased local androgen activity can stimulate these glands to produce more sebum, which can exacerbate the problem of clogged pores.

Androgenetic Alopecia and Sebum Production: Androgenetic alopecia (AGA), a common form of hair loss, often involves hormonal influences that affect hair follicles and sebaceous glands. In AGA, the sensitivity of hair follicles to androgens leads to the miniaturization of hair follicles and reduced hair growth. Despite the reduced hair production, sebaceous glands continue to secrete sebum, contributing to the accumulation of sebum plugs. Additionally, androgens can stimulate sebaceous glands to enlarge and to produce excess sebum, further aggravating the condition.

Hormonal Influences: Sebum production is tightly regulated by hormonal factors, especially androgens like testosterone and dihydrotestosterone (DHT). These hormones increase sebaceous gland activity, leading to higher sebum output. Conditions such as polycystic ovary syndrome (PCOS) and other hormonal imbalances can exacerbate sebum production, contributing to the formation of sebum plugs. In women, hormonal fluctuations during menstruation, pregnancy, and menopause can also affect sebum production and increase or decrease the chances of sebum plug development.

Microbiome and Inflammation: The scalp microbiome, composed of various microorganisms including bacteria and fungi, plays a significant role in scalp health. An imbalance in the microbiome can lead to inflammatory conditions like seborrheic dermatitis and dandruff, which can exacerbate the formation of sebum plugs. Malassezia, a yeast commonly found on the scalp, thrives on sebum and can contribute to inflammation and scalp disorders when overgrown.

Genetic Predisposition: Genetics influence both hair loss patterns and sebaceous gland activity. Individuals with a family history of androgenetic alopecia or other hair loss conditions may also be more prone to developing sebum plugs due to inherited traits affecting follicular activity and sebaceous gland function.

Environmental Factors: Environmental factors such as humidity, temperature, and pollution can affect sebum production and scalp health. High humidity can increase sebum production, while pollution might contribute to the accumulation of debris and blockage of hair follicles, leading to sebum plugs.

Stress and Lifestyle: Stress is known to influence hormonal levels, particularly cortisol, which can indirectly affect sebaceous gland activity. Chronic stress can exacerbate conditions like androgenetic alopecia and may also increase the likelihood of developing sebum plugs. Adequate sleep, regular exercise, and stress management techniques can support overall scalp health.

Management Strategies: Addressing scalp pimples involves managing sebum production and maintaining scalp hygiene. Here are some potential strategies:

  1. Regular Washing: Regular cleansing of the scalp can help remove excess sebum and prevent the formation of plugs. Using a mild shampoo is recommended to avoid irritating the scalp. Scalp skin irritation in itself can lead to increased sebum plug formation.
  2. Exfoliation: Gentle exfoliation can help remove dead skin cells and prevent them from clogging hair follicles. Shampoo products containing salicylic acid or glycolic acid can be beneficial. Several are available, usually advertised as anti-dandruff shampoos.
  3. Topical Treatments: Certain topical treatments can help regulate sebum production and improve scalp health. For example, ketoconazole shampoos have anti-inflammatory and anti-androgenic properties that can be helpful in managing sebum production.
  4. Diet and Lifestyle: A balanced diet and healthy lifestyle can support overall scalp health. Ensuring adequate intake of vitamins and minerals such as zinc, vitamin A, and omega-3 fatty acids can help regulate sebum production. Several dietary foods have been shown to be linked to increased sebum production, particularly sugary foods and refined carbohydrates.
  5. Medical Interventions: In a few cases, medical treatments such as anti-androgens or retinoids may be necessary. Consulting a dermatologist or trichologist can provide personalized treatment options.
  6. Natural Remedies: Some natural remedies, such as tea tree oil, have antimicrobial and anti-inflammatory properties that can indirectly help manage sebum plugs. However, these should be used with caution and under the guidance of a healthcare professional to avoid irritation or allergic reactions.

Scalp Hygiene and Hair Care Practices: While proper scalp hygiene is crucial for managing sebum plugs, over-washing can strip the scalp of natural oils, leading to a compensatory increase in sebum production. Using a mild, pH-balanced shampoo can help maintain the scalp’s natural barrier. Additionally, avoiding heavy, oily hair products that can contribute to follicular build up and blockage can be helpful.

Conclusion: Scalp pimples that can be scratched out, often containing hardened sebum and occasionally attached hair, are a common issue linked to various forms of hair loss, including androgenetic alopecia. These pimples are primarily composed of sebum, keratinized cell debris, and hair follicle root sheath cell material. Factors such as inactive hair follicles, improper hair growth, and androgen sensitivity contribute to their formation. Managing these pimples involves regular scalp cleansing, gentle exfoliation, and sometimes topical or medical treatments. Understanding the underlying causes and adopting appropriate strategies can help alleviate this condition and promote healthier scalp and hair.

Bibliography

1.
Braun-Falco O, Plewig G, Wolff HH, Burgdorf WHC. Diseases of the Sebaceous Glands. In: Braun-Falco O, Plewig G, Wolff HH, Burgdorf WHC, editors. Dermatology. Berlin, Heidelberg: Springer; 2000. p. 1051–81.
1.
Thiboutot D. Regulation of human sebaceous glands. J Invest Dermatol. 2004 Jul;123(1):1–12.
1.
Burkhart CG, Burkhart CN. Expanding the microcomedone theory and acne therapeutics: Propionibacterium acnes biofilm produces biological glue that holds corneocytes together to form plug. J Am Acad Dermatol. 2007 Oct;57(4):722–4.
1.
Rossi A, Fortuna MC, Pranteda G, Garelli V, Di Nunno D, Mari E, et al. Clinical, Histological and Trichoscopic Correlations in Scalp Disorders. Dermatology. 2015 Jul 2;231(3):201–8.
1.
Suzuki K, Inoue M, Cho O, Mizutani R, Shimizu Y, Nagahama T, et al. Scalp Microbiome and Sebum Composition in Japanese Male Individuals with and without Androgenetic Alopecia. Microorganisms. 2021 Oct;9(10):2132.
1.
Anastassakis K. Shampoos and AGA/FPHL. In: Anastassakis K, editor. Androgenetic Alopecia From A to Z: Vol3 Hair Restoration Surgery, Alternative Treatments, and Hair Care. Cham: Springer International Publishing; 2023. p. 761–4.